Diagnosis and treatment of alpha-gal syndrome
What is alpha Gal syndrome?
Alpha-gal syndrome, also known as alpha-gal allergy, is an immunological reaction of the body to the carbohydrate alpha-galactose, which is found in certain meat products. People with this allergy can develop an allergic reaction after eating meat from mammals such as beef, pork or sheep. This reaction can range from mild symptoms such as a skin rash and stomach discomfort to more severe symptoms such as anaphylaxis. This allergy is often caused by a tick bite, as ticks can transmit the alpha-gal molecule.
Course of Alpha Gal syndrome
Symptoms of alpha-gal syndrome: Find out more
Alpha Gal syndrome can cause symptoms in the gastrointestinal tract, such as abdominal pain, diarrhea, nausea or vomiting. Skin rashes, reddening of the skin, swelling of the face or fainting spells are also possible.
Is there a test for alpha-gal syndrome?
Yes, a blood test can detect immunoglobulin E (IgE) antibodies against alpha-gal. If these antibodies are present, there is a possibility of alpha-gal allergy. Symptoms should improve if you avoid eating meat from mammals.
What are treatment options for alpha-gal syndrome?
The main treatment for alpha-gal allergies is to avoid foods that contain alpha-gal, such as meat and products made from it. Some patients also have symptoms after eating dairy products or gelatine.
What animal products can I eat with alpha-gal syndrome?
Poultry, turkey and fish are safe options as they are not mammalian.
What are the causes of the allergy?
Some people develop the allergy after a tick bite, especially from the lone star tick in the US. Avoiding tick bites is important as the allergy may subside if no further bites occur.
Am I really allergic?
Alpha-gal allergy does not always cause immediate symptoms after eating meat. There are different triggers, and not everyone has symptoms after eating meat.
Medications with alpha-gal
Some medications contain alpha-gal, including the cancer drug cetuximab and certain enzyme preparations.
More information on alpha-gal syndrome?
For further information and advice on alpha-gal syndrome and gastrointestinal symptoms, please contact Vivomed -Gastroenterology Bern.